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An enhanced genetic model of colorectal cancer progression history
BACKGROUND: The classical genetic model of colorectal cancer presents APC mutations as the earliest genomic alterations, followed by KRAS and TP53 mutations. However, the timing and relative order of clonal expansion and other types of genomic alterations, such as genomic rearrangements, are still u...
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| Publicado no: | Genome Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6694562/ https://ncbi.nlm.nih.gov/pubmed/31416464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1782-4 |
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