Genetic reconstruction of individual colorectal tumor histories

It is difficult to observe human tumor progression as precursor lesions are systematically removed. Alternatives to direct observations, commonly used to reveal the hidden past of species and populations, are sequence comparisons or molecular clocks. Noncoding microsatellite (MS) loci were employed...

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Main Authors: Tsao, Jen-Lan, Yatabe, Yasushi, Salovaara, Reijo, Järvinen, Heikki J., Mecklin, Jukka-Pekka, Aaltonen, Lauri A., Tavaré, Simon, Shibata, Darryl
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15581/
https://ncbi.nlm.nih.gov/pubmed/10655514
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