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Genetic reconstruction of individual colorectal tumor histories

It is difficult to observe human tumor progression as precursor lesions are systematically removed. Alternatives to direct observations, commonly used to reveal the hidden past of species and populations, are sequence comparisons or molecular clocks. Noncoding microsatellite (MS) loci were employed...

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Main Authors: Tsao, Jen-Lan, Yatabe, Yasushi, Salovaara, Reijo, Järvinen, Heikki J., Mecklin, Jukka-Pekka, Aaltonen, Lauri A., Tavaré, Simon, Shibata, Darryl
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC15581/
https://ncbi.nlm.nih.gov/pubmed/10655514
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