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Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway

BACKGROUND: The PINK1:Parkin pathway regulates the autophagic removal of damaged and dysfunctional mitochondria. While the response of this pathway to complete loss of ΔΨm, as caused by high concentrations of mitochondrial ionophores, has been well characterized, it remains unclear how the pathway m...

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Detalhes bibliográficos
Publicado no:BMC Mol Cell Biol
Main Authors: Bowling, J. Logan, Skolfield, Mary Catherine, Riley, Wesley A., Nolin, Andrew P., Wolf, Larissa C., Nelson, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694515/
https://ncbi.nlm.nih.gov/pubmed/31412778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-019-0220-5
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