Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts

Fibroblast growth factor 21 (FGF21) is a metabolic hormone having anti-oxidative and anti-hypertrophic effects. However, the regulation of FGF21 expression during acute myocardial infarction (AMI) remains unclear. We tested blood samples from 50 patients with AMI and 43 patients with stable angina p...

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Published in:Sci Rep
Main Authors: Sunaga, Hiroaki, Koitabashi, Norimichi, Iso, Tatsuya, Matsui, Hiroki, Obokata, Masaru, Kawakami, Ryo, Murakami, Masami, Yokoyama, Tomoyuki, Kurabayashi, Masahiko
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694166/
https://ncbi.nlm.nih.gov/pubmed/31413360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48356-1
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