Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes

BACKGROUND: Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (ob) and the leptin receptor (ob-R) in the pressure-overloaded rat heart. We als...

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Main Authors: Matsui, Hiroki, Yokoyama, Tomoyuki, Tanaka, Chie, Sunaga, Hiroaki, Koitabashi, Norimichi, Takizawa, Takako, Arai, Masashi, Kurabayashi, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543168/
https://ncbi.nlm.nih.gov/pubmed/23270329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-13-37
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