Stearoyl-CoA Desaturase-1 (SCD1) Augments Saturated Fatty Acid-Induced Lipid Accumulation and Inhibits Apoptosis in Cardiac Myocytes

Mismatch between the uptake and utilization of long-chain fatty acids in the myocardium leads to abnormally high intracellular fatty acid concentration, which ultimately induces myocardial dysfunction. Stearoyl-Coenzyme A desaturase-1 (SCD1) is a rate-limiting enzyme that converts saturated fatty ac...

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Detalhes bibliográficos
Main Authors: Matsui, Hiroki, Yokoyama, Tomoyuki, Sekiguchi, Kenichi, Iijima, Daisuke, Sunaga, Hiroaki, Maniwa, Moeno, Ueno, Manabu, Iso, Tatsuya, Arai, Masashi, Kurabayashi, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297642/
https://ncbi.nlm.nih.gov/pubmed/22413010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033283
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