An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters

Anaerobic bacteria represent an overlooked rich source of biological and chemical diversity. Due to the challenge of cultivation and genetic intractability, assessing the capability of their biosynthetic gene clusters (BGCs) for secondary metabolite production requires an efficient heterologous expr...

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Publicat a:Nat Commun
Autors principals: Hao, Tingting, Xie, Zhoujie, Wang, Min, Liu, Liwei, Zhang, Yuwei, Wang, Weicang, Zhang, Zhao, Zhao, Xuejin, Li, Pengwei, Guo, Zhengyan, Gao, Shushan, Lou, Chunbo, Zhang, Guodong, Merritt, Justin, Horsman, Geoff P., Chen, Yihua
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694145/
https://ncbi.nlm.nih.gov/pubmed/31413323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11673-0
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