SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity

Proinflammatory activation and accumulation of adipose tissue macrophages (ATMs) are associated with increased risk of insulin resistance in obesity. Here, we described the previously unidentified role of selenocysteine insertion sequence–binding protein 2 (SBP2) in maintaining insulin sensitivity i...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Wang, Ning, Tan, Hor-Yue, Li, Sha, Wang, Di, Xu, Yu, Zhang, Cheng, Xia, Wen, Che, Chi-Ming, Feng, Yibin
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693917/
https://ncbi.nlm.nih.gov/pubmed/31453320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav0198
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