SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity

Proinflammatory activation and accumulation of adipose tissue macrophages (ATMs) are associated with increased risk of insulin resistance in obesity. Here, we described the previously unidentified role of selenocysteine insertion sequence–binding protein 2 (SBP2) in maintaining insulin sensitivity i...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Wang, Ning, Tan, Hor-Yue, Li, Sha, Wang, Di, Xu, Yu, Zhang, Cheng, Xia, Wen, Che, Chi-Ming, Feng, Yibin
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693917/
https://ncbi.nlm.nih.gov/pubmed/31453320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav0198
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