SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity

Proinflammatory activation and accumulation of adipose tissue macrophages (ATMs) are associated with increased risk of insulin resistance in obesity. Here, we described the previously unidentified role of selenocysteine insertion sequence–binding protein 2 (SBP2) in maintaining insulin sensitivity i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Adv
Egile Nagusiak: Wang, Ning, Tan, Hor-Yue, Li, Sha, Wang, Di, Xu, Yu, Zhang, Cheng, Xia, Wen, Che, Chi-Ming, Feng, Yibin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Association for the Advancement of Science 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693917/
https://ncbi.nlm.nih.gov/pubmed/31453320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav0198
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