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Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia

Pneumonia poses profound health threats to preterm infants. Alveolar macrophages (AMs) eliminate inhaled pathogens while maintaining surfactant homeostasis. As AM development only occurs perinatally, therapies that accelerate AM maturation in preterms may improve outcomes. We tested therapeutic resc...

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Pubblicato in:Sci Adv
Autori principali: Todd, Elizabeth M., Ramani, Rashmi, Szasz, Taylor P., Morley, S. Celeste
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693910/
https://ncbi.nlm.nih.gov/pubmed/31453341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax3387
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