Lower respiratory tract delivery, airway clearance, and preclinical efficacy of inhaled GM-CSF in a postinfluenza pneumococcal pneumonia model

Inhaled granulocyte/macrophage colony-stimulating factor (GM-CSF) shows promise as a therapeutic to treat viral and bacterial pneumonia, but no mouse model of inhaled GM-CSF has been described. We sought to 1) develop a mouse model of aerosolized recombinant mouse GM-CSF administration and 2) invest...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Umstead, Todd M., Hewage, Eranda Kurundu, Mathewson, Margaret, Beaudoin, Sarah, Chroneos, Zissis C., Wang, Ming, Halstead, E. Scott
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191485/
https://ncbi.nlm.nih.gov/pubmed/31994895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00296.2019
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge