Observation of preQ(1)-II riboswitch dynamics using single-molecule FRET

PreQ(1) riboswitches regulate the synthesis of the hypermodified tRNA base queuosine by sensing the pyrrolopyrimidine metabolite preQ(1). Here, we use single-molecule FRET to interrogate the structural dynamics of apo and preQ(1)-bound states of the preQ(1)-II riboswitch from Lactobacillus rhamnosus...

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Bibliographic Details
Published in:RNA Biol
Main Authors: Warnasooriya, Chandani, Ling, Clarence, Belashov, Ivan A., Salim, Mohammad, Wedekind, Joseph E., Ermolenko, Dmitri N.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
Subjects:
Brief Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693549/
https://ncbi.nlm.nih.gov/pubmed/30328747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1536591
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