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Structure of a class II preQ(1) riboswitch reveals ligand recognition by a new fold
PreQ(1) riboswitches regulate genes by binding the pyrrolopyrimidine intermediate preQ(1) during biosynthesis of the essential tRNA base queuosine. We report the first preQ(1)-II riboswitch structure at 2.3 Å resolution, which uses a novel fold to achieve effector recognition at the confluence of a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661761/ https://ncbi.nlm.nih.gov/pubmed/23584677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1231 |
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