Single transcriptional and translational preQ(1) riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure

Riboswitches are structural elements in the 5′ untranslated regions of many bacterial messenger RNAs that regulate gene expression in response to changing metabolite concentrations by inhibition of either transcription or translation initiation. The preQ(1) (7-aminomethyl-7-deazaguanine) riboswitch...

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Detalhes bibliográficos
Main Authors: Suddala, Krishna C., Rinaldi, Arlie J., Feng, Jun, Mustoe, Anthony M., Eichhorn, Catherine D., Liberman, Joseph A., Wedekind, Joseph E., Al-Hashimi, Hashim M., Brooks, Charles L., Walter, Nils G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905878/
https://ncbi.nlm.nih.gov/pubmed/24003028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt798
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