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Endothelium-dependent impairments to cerebral vascular reactivity with type 2 diabetes mellitus in the Goto-Kakizaki rat

Type 2 diabetes mellitus (T2DM) is a prevalent pathology associated with elevated cerebrovascular disease risk. We determined wall mechanics and vascular reactivity in ex vivo middle cerebral arteries (MCA) from male Goto-Kakizaki rats (GK; ~17 wk old) versus control Wistar Kyoto rats (WKY) to test...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Regul Integr Comp Physiol
Main Authors: Halvorson, Brayden D., Whitehead, Shawn N., McGuire, John J., Wiseman, Robert W., Frisbee, Jefferson C.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692758/
https://ncbi.nlm.nih.gov/pubmed/31091154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00088.2019
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