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Cardioprotective roles of sestrin 1 and sestrin 2 against doxorubicin cardiotoxicity

Doxorubicin is a chemotherapy medication widely used to treat a variety of cancers. Even though it offers one of the most effective anti-cancer treatments, its clinical use is limited because of its strong cardiotoxicity that can lead to fatal conditions. Here, we show that sestrin 1 and sestrin 2,...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Li, Ruiting, Huang, Yin, Semple, Ian, Kim, Myungjin, Zhang, Zunjian, Lee, Jun Hee
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692737/
https://ncbi.nlm.nih.gov/pubmed/31026186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00008.2019
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