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Cardioprotective Roles of β-Hydroxybutyrate Against Doxorubicin Induced Cardiotoxicity

Background: β-Hydroxybutyrate (BHB) is produced by fatty acid oxidation in the liver under the fasting state and confirmed to play a cardioprotective role in ischemia and hypertensive settings. Doxorubicin (DOX) is an effective chemotherapeutic drug, but limited by serious irreversible cardiotoxicit...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Liu, Yihai, Wei, Xuan, Wu, Mingyue, Xu, Jiamin, Xu, Biao, Kang, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082360/
https://ncbi.nlm.nih.gov/pubmed/33935690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.603596
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