Analysis of Cre-mediated genetic deletion of Gdf11 in cardiomyocytes of young mice

Administration of active growth differentiation factor 11 (GDF11) to aged mice can reduce cardiac hypertrophy, and low serum levels of GDF11 measured together with the related protein, myostatin (also known as GDF8), predict future morbidity and mortality in coronary heart patients. Using mice with...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Garbern, Jessica, Kristl, Amy C., Bassaneze, Vinicius, Vujic, Ana, Schoemaker, Henk, Sereda, Rebecca, Peng, Liming, Ricci-Blair, Elisabeth M., Goldstein, Jill M., Walker, Ryan G., Bhasin, Shalender, Wagers, Amy J., Lee, Richard T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692736/
https://ncbi.nlm.nih.gov/pubmed/31125255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00615.2018
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