Overexpression of SMYD3 in Ovarian Cancer is Associated with Ovarian Cancer Proliferation and Apoptosis via Methylating H3K4 and H4K20

Background: Epigenetic regulation has been verified as a key mechanism in tumorigenesis. SET and MYND domain-containing protein 3 (SMYD3), a histone methyltransferase, is a promising epigenetic therapeutic target and is overexpressed in numerous human tumors. SMYD3 can promote oncogenic progression...

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Pubblicato in:J Cancer
Autori principali: Jiang, Yahui, Lyu, Tianjiao, Che, Xiaoxia, Jia, Nan, Li, Qin, Feng, Weiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692630/
https://ncbi.nlm.nih.gov/pubmed/31417652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.29861
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