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Structure-based identification of a potential non-catalytic binding site for rational drug design in the fructose 1,6-biphosphate aldolase from Giardia lamblia

Giardia lamblia is the causal agent of giardiasis, one of the most prevalent parasitosis in the world. Even though effective pharmacotherapies against this parasite are available, the disadvantages associated with its use call for the development of new antigiardial compounds. Based on the Giardia d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Méndez, Sara-Teresa, Castillo-Villanueva, Adriana, Martínez-Mayorga, Karina, Reyes-Vivas, Horacio, Oria-Hernández, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692403/
https://ncbi.nlm.nih.gov/pubmed/31409864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48192-3
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