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Specific Substates of Ras to Interact with GAPs and Effectors: Revealed by Theoretical Simulations and FTIR Experiments

The oncogenic Ras protein adopts various specific conformational states to execute its function in signal transduction. The large number of Ras structures obtained from X-ray and NMR experiments illustrate the diverse conformations that Ras adopts. It is difficult, however, to connect specific struc...

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Detalles Bibliográficos
Publicado en:J Phys Chem Lett
Main Authors: Li, Yang, Zhang, Yuwei, Großerüschkamp, Frederick, Stephan, Sara, Cui, Qiang, Kötting, Carsten, Xia, Fei, Gerwert, Klaus
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692134/
https://ncbi.nlm.nih.gov/pubmed/29488771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.8b00342
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