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Specific Substates of Ras to Interact with GAPs and Effectors: Revealed by Theoretical Simulations and FTIR Experiments

The oncogenic Ras protein adopts various specific conformational states to execute its function in signal transduction. The large number of Ras structures obtained from X-ray and NMR experiments illustrate the diverse conformations that Ras adopts. It is difficult, however, to connect specific struc...

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Dettagli Bibliografici
Pubblicato in:J Phys Chem Lett
Autori principali: Li, Yang, Zhang, Yuwei, Großerüschkamp, Frederick, Stephan, Sara, Cui, Qiang, Kötting, Carsten, Xia, Fei, Gerwert, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692134/
https://ncbi.nlm.nih.gov/pubmed/29488771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.8b00342
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