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Specific Substates of Ras to Interact with GAPs and Effectors: Revealed by Theoretical Simulations and FTIR Experiments

The oncogenic Ras protein adopts various specific conformational states to execute its function in signal transduction. The large number of Ras structures obtained from X-ray and NMR experiments illustrate the diverse conformations that Ras adopts. It is difficult, however, to connect specific struc...

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Bibliografski detalji
Izdano u:J Phys Chem Lett
Glavni autori: Li, Yang, Zhang, Yuwei, Großerüschkamp, Frederick, Stephan, Sara, Cui, Qiang, Kötting, Carsten, Xia, Fei, Gerwert, Klaus
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692134/
https://ncbi.nlm.nih.gov/pubmed/29488771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.8b00342
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