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Specific Substates of Ras to Interact with GAPs and Effectors: Revealed by Theoretical Simulations and FTIR Experiments
The oncogenic Ras protein adopts various specific conformational states to execute its function in signal transduction. The large number of Ras structures obtained from X-ray and NMR experiments illustrate the diverse conformations that Ras adopts. It is difficult, however, to connect specific struc...
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| Pubblicato in: | J Phys Chem Lett |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692134/ https://ncbi.nlm.nih.gov/pubmed/29488771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.8b00342 |
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