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Ddc2(ATRIP) promotes Mec1(ATR) activation at RPA-ssDNA tracts
The DNA damage checkpoint response is controlled by the phosphatidylinositol 3-kinase-related kinases (PIKK), including ataxia telangiectasia-mutated (ATM) and ATM and Rad3-related (ATR). ATR forms a complex with its partner ATRIP. In budding yeast, ATR and ATRIP correspond to Mec1 and Ddc2, respect...
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| Publicado en: | PLoS Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692047/ https://ncbi.nlm.nih.gov/pubmed/31369547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008294 |
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