Inhibition of proliferation and migration of tumor cells through phenylboronic acid-functionalized polyamidoamine-mediated delivery of a therapeutic DNAzyme Dz13

BACKGROUND: The phenylboronic acid-functionalized polyamidoamine (PP) was employed as a gene carrier for Dz13 delivery, inducing an obvious anticancer response. MATERIALS AND METHODS: The Dz13 condensation ability of PP was evaluated through gel retardation assay. The cellular uptake mechanism of PP...

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Publicado en:Int J Nanomedicine
Autores principales: Yang, Jiebing, Zhang, Jiayuan, Xing, Jiakai, Shi, Zhiyuan, Han, Haobo, Li, Quanshun
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove 2019
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691943/
https://ncbi.nlm.nih.gov/pubmed/31496692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S211744
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