Inhibition of cell proliferation and migration through nucleobase-modified polyamidoamine-mediated p53 delivery

INTRODUCTION: The nucleobase 2-amino-6-chloropurine-modified polyamidoamine (AP-PAMAM) was used as a carrier for p53 gene delivery to achieve the antitumor effects. METHODS AND MATERIALS: The condensation of p53 plasmid was studied through gel retardation assay, and the transfection efficiency was e...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Han, Haobo, Chen, Wenqi, Yang, Jiebing, Liang, Xiao, Wang, Yudi, Li, Quanshun, Yang, Yan, Li, Kun
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846749/
https://ncbi.nlm.nih.gov/pubmed/29563788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S146917
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