Delivery of DNAzyme targeting aurora kinase A to inhibit the proliferation and migration of human prostate cancer

Herein, a polyethylenimine derivative N-acetyl-l-leucine-polyethylenimine (N-Ac-l-Leu-PEI) was employed as a carrier to achieve the delivery of DNAzyme targeting aurora kinase A using PC-3 cell as a model. Flow cytometry and confocal laser scanning microscopy demonstrated that the derivative could r...

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Sparad:
Bibliografiska uppgifter
I publikationen:Int J Nanomedicine
Huvudupphovsmän: Xing, Zhen, Gao, Sai, Duan, Yan, Han, Haobo, Li, Li, Yang, Yan, Li, Quanshun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2015
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583550/
https://ncbi.nlm.nih.gov/pubmed/26425080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S90559
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