Age-Based Dynamics of a Stable Circulating Cd8 T Cell Repertoire Component

T-cell memory to pathogens can be envisioned as a receptor-based imprint of the pathogenic environment on the naïve repertoire of clonotypes. Recurrent exposures to a pathogen inform and reinforce memory, leading to a mature state. The complexity and temporal stability of this system in man is only...

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Publicado en:Front Immunol
Autores principales: Naumova, Elena N., Yassai, Maryam B., Demos, Wendy, Reed, Erica, Unruh, Melissa, Haribhai, Dipica, Williams, Calvin B., Naumov, Yuri N., Gorski, Jack
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691812/
https://ncbi.nlm.nih.gov/pubmed/31447830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01717
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