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Structural and mechanistic implications of rearrangement frequencies within human TCR BV genes

The T cell repertoire is a function of thymic V(D)J rearrangement and of peripheral selection. The mature repertoire embodies TCR sequences that are important for survival and can identify important structural aspects of the TCR. Analysis of the circulating BV19 CD8 T cell TCR repertoire showed that...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Yassai, Maryam B., Demos, Wendy, Gorski, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659713/
https://ncbi.nlm.nih.gov/pubmed/28659354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601450
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