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The T cell receptor repertoires of regulatory and conventional T cells specific for the same foreign antigen are distinct()

The relationship between the TCR repertoires of natural regulatory T (nT(reg)) and conventional T (T(conv)) cells capable of responding to the same antigenic epitope is unknown. Here, we used TCRβ-chain transgenic mice to generate polyclonal nT(reg) and T(conv) cell populations specific for a foreig...

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Detalhes bibliográficos
Main Authors: Relland, Lance M., Williams, Jason B., Relland, Gwendolyn N., Haribhai, Dipica, Ziegelbauer, Jennifer, Yassai, Maryam, Gorski, Jack, Williams, Calvin B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538134/
https://ncbi.nlm.nih.gov/pubmed/22933635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102646
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