Exclusive Temporal Stimulation of IL-10 Expression in LPS-Stimulated Mouse Macrophages by cAMP Inducers and Type I Interferons

Expression of the key anti-inflammatory cytokine IL-10 in lipopolysaccharide (LPS)-stimulated macrophages is mediated by a delayed autocrine/paracrine loop of type I interferons (IFN) to ensure timely attenuation of inflammation. We have previously shown that cAMP synergizes with early IL-10 express...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ernst, Orna, Glucksam-Galnoy, Yifat, Bhatta, Bibek, Athamna, Muhammad, Ben-Dror, Iris, Glick, Yair, Gerber, Doron, Zor, Tsaffrir
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691811/
https://ncbi.nlm.nih.gov/pubmed/31447835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01788
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