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The cAMP Pathway Amplifies Early MyD88-Dependent and Type I Interferon-Independent LPS-Induced Interleukin-10 Expression in Mouse Macrophages

Interleukin-10 (IL-10) is a key anti-inflammatory cytokine, secreted by macrophages and other immune cells to attenuate inflammation. Autocrine type I interferons (IFNs) largely mediate the delayed expression of IL-10 by LPS-stimulated macrophages. We have previously shown that IL-10 is synergistica...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Ernst, Orna, Glucksam-Galnoy, Yifat, Athamna, Muhammad, Ben-Dror, Iris, Ben-Arosh, Hadar, Levy-Rimler, Galit, Fraser, Iain D. C., Zor, Tsaffrir
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501241/
https://ncbi.nlm.nih.gov/pubmed/31148944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3451461
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