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Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies

Pyrazolylphthalimide derivative 4 was synthesized and reacted with different reagents to afford the target compounds imidazopyrazoles 5-7, pyrazolopyrimidines 9, 12, 14 and pyrazolotriazines 16, 17 containing phthalimide moiety. The prepared compounds were established by different spectral data and...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Othman, Ismail M. M., Gad-Elkareem, Mohamed A. M., El-Naggar, Mohamed, Nossier, Eman S., Amr, Abd El-Galil E.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691772/
https://ncbi.nlm.nih.gov/pubmed/31287341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1637861
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