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Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2
Protein arginine deiminases (PADs) are calcium-dependent enzymes that mediate the post-translational conversion of arginine into citrulline. Dysregulated PAD activity is associated with numerous autoimmune disorders and cancers. In breast cancer, PAD2 citrullinates histone H3R26 and activates the tr...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6691507/ https://ncbi.nlm.nih.gov/pubmed/31243954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00225 |
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