The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs)

Citrullination is the post-translational hydrolysis of peptidyl-arginines to form peptidyl-citrulline, a reaction that is catalyzed by the protein arginine deiminases (PADs), a family of calcium-regulated enzymes. Aberrantly increased protein citrullination is associated with a slew of autoimmune di...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Nemmara, Venkatesh V., Subramanian, Venkataraman, Muth, Aaron, Mondal, Santanu, Salinger, Ari J., Maurais, Aaron J., Tilvawala, Ronak, Weerapana, Eranthie, Thompson, Paul R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862558/
https://ncbi.nlm.nih.gov/pubmed/29341591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00957
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