Cinnamonitrile Adjuvants Restore Susceptibility to β-Lactams against Methicillin-Resistant Staphylococcus aureus

[Image: see text] β-Lactams are used routinely to treat Staphylococcus aureus infections. However, the emergence of methicillin-resistant S. aureus (MRSA) renders them clinically precarious. We describe a class of cinnamonitrile adjuvants that restore the activity of oxacillin (a penicillin member o...

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Publicat a:ACS Med Chem Lett
Autors principals: Speri, Enrico, Kim, Choon, De Benedetti, Stefania, Qian, Yuanyuan, Lastochkin, Elena, Fishovitz, Jennifer, Fisher, Jed F., Mobashery, Shahriar
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691485/
https://ncbi.nlm.nih.gov/pubmed/31413798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00169
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