Discrete steps in sensing of β-lactam antibiotics by the BlaR1 protein of the methicillin-resistant Staphylococcus aureus bacterium

Chemical sensing by cell-surface receptors to effect signal transduction is a ubiquitous biological event. Despite extensive structural biochemical study, detailed knowledge of how signal transduction occurs is largely lacking. We report herein a kinetic and structural study, obtained by stopped-flo...

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Autores principales: Thumanu, Kanjana, Cha, Jooyoung, Fisher, Jed F., Perrins, Richard, Mobashery, Shahriar, Wharton, Christopher
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502283/
https://ncbi.nlm.nih.gov/pubmed/16815972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601971103
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