Phosphorylation of BlaR1 in Manifestation of Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus and its Abrogation by Small Molecules

Methicillin-resistant Staphylococcus aureus (MRSA), an important human pathogen, has evolved an inducible mechanism for resistance to β-lactam antibiotics. We report herein that the integral membrane protein BlaR1, the β-lactam sensor/signal transducer protein, is phosphorylated on exposure to β-lac...

Full description

Saved in:
Bibliographic Details
Published in:ACS Infect Dis
Main Authors: Boudreau, Marc A., Fishovitz, Jennifer, Llarrull, Leticia I., Xiao, Qiaobin, Mobashery, Shahriar
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022795/
https://ncbi.nlm.nih.gov/pubmed/27623311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00086
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items