Myeloid maturation potentiates STAT3-mediated atypical IFN-γ signaling and upregulation of PD-1 ligands in AML and MDS

Interferon (IFN)-γ is the major mediator of anti-tumor immune responses; nevertheless, cancer cells use intrigue strategies to alter IFN-γ signaling and avoid elimination. Understanding the immune regulatory mechanisms employed by acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) cells...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Yoyen-Ermis, Digdem, Tunali, Gurcan, Tavukcuoglu, Ece, Horzum, Utku, Ozkazanc, Didem, Sutlu, Tolga, Buyukasik, Yahya, Esendagli, Gunes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691003/
https://ncbi.nlm.nih.gov/pubmed/31406210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48256-4
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi