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Functional exhaustion of CD4(+) T cells induced by co‐stimulatory signals from myeloid leukaemia cells

To cope with immune responses, tumour cells implement elaborate strategies such as adaptive resistance and induction of T‐cell exhaustion. T‐cell exhaustion has been identified as a state of hyporesponsiveness that arises under continuous antigenic stimulus. Nevertheless, contribution of co‐stimulat...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Ozkazanc, Didem, Yoyen‐Ermis, Digdem, Tavukcuoglu, Ece, Buyukasik, Yahya, Esendagli, Gunes
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095494/
https://ncbi.nlm.nih.gov/pubmed/27565576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12665
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