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Cancer Testis Antigen Promotes Triple Negative Breast Cancer Metastasis and is Traceable in the Circulating Extracellular Vesicles

Triple negative breast cancer (TNBC) has poor survival, exhibits rapid metastases, lacks targeted therapies and reliable prognostic markers. Here, we examined metastasis promoting role of cancer testis antigen SPANXB1 in TNBC and its utility as a therapeutic target and prognostic biomarker. Expressi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kannan, Anbarasu, Philley, Julie V., Hertweck, Kate L., Ndetan, Harrison, Singh, Karan P., Sivakumar, Subramanium, Wells, Robert B., Vadlamudi, Ratna K., Dasgupta, Santanu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690992/
https://ncbi.nlm.nih.gov/pubmed/31406142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48064-w
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