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Cancer Testis Antigen Promotes Triple Negative Breast Cancer Metastasis and is Traceable in the Circulating Extracellular Vesicles

Triple negative breast cancer (TNBC) has poor survival, exhibits rapid metastases, lacks targeted therapies and reliable prognostic markers. Here, we examined metastasis promoting role of cancer testis antigen SPANXB1 in TNBC and its utility as a therapeutic target and prognostic biomarker. Expressi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kannan, Anbarasu, Philley, Julie V., Hertweck, Kate L., Ndetan, Harrison, Singh, Karan P., Sivakumar, Subramanium, Wells, Robert B., Vadlamudi, Ratna K., Dasgupta, Santanu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690992/
https://ncbi.nlm.nih.gov/pubmed/31406142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48064-w
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