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Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression

Mitochondria (mt) encoded respiratory complex-I (RCI) mutations and their pathogenicity remain largely unknown in prostate cancer (PCa). Little is known about the role of mtDNA loss on mt integrity in PCa. We determined mtDNA mutation in human and mice PCa and assessed the impact of mtDNA depletion...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: PHILLEY, JULIE V., KANNAN, ANBARASU, QIN, WENYI, SAUTER, EDWARD R., IKEBE, MITSUO, HERTWECK, KATE L., TROYER, DEAN A., SEMMES, OLIVER J., DASGUPTA, SANTANU
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741292/
https://ncbi.nlm.nih.gov/pubmed/26530043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25240
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