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Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression

Mitochondria (mt) encoded respiratory complex-I (RCI) mutations and their pathogenicity remain largely unknown in prostate cancer (PCa). Little is known about the role of mtDNA loss on mt integrity in PCa. We determined mtDNA mutation in human and mice PCa and assessed the impact of mtDNA depletion...

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Bibliografske podrobnosti
izdano v:J Cell Physiol
Main Authors: PHILLEY, JULIE V., KANNAN, ANBARASU, QIN, WENYI, SAUTER, EDWARD R., IKEBE, MITSUO, HERTWECK, KATE L., TROYER, DEAN A., SEMMES, OLIVER J., DASGUPTA, SANTANU
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741292/
https://ncbi.nlm.nih.gov/pubmed/26530043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25240
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