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Identification of methotrexate as a heterochromatin-promoting drug

Heterochromatin is a tightly packed form of DNA involved in gene silencing, chromosome segregation, and protection of genome stability. Heterochromatin is becoming more recognized in tumor suppression and may thus serve as a potential target for cancer therapy. However, to date there are no drugs th...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Loyola, Andre C., Zhang, Lin, Shang, Robin, Dutta, Pranabananda, Li, Jinghong, Li, Willis X.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690983/
https://ncbi.nlm.nih.gov/pubmed/31406262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48137-w
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