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Atorvastatin increases the production of proinflammatory cytokines and decreases the survival of Escherichia coli-infected mice
To assess whether the immunosuppressive effects of atorvastatin outweigh its antibacterial ones in an infection, mice were infected with Escherichia coli and administered atorvastatin; survival rates were then monitored. Mice treated with atorvastatin post-infection showed a remarkable decrease in t...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690901/ https://ncbi.nlm.nih.gov/pubmed/31406240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48282-2 |
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