Decrease in Shiga toxin expression using a minimal inhibitory concentration of rifampicin followed by bactericidal gentamicin treatment enhances survival of Escherichia coli O157:H7-infected BALB/c mice

BACKGROUND: Treatment of Escherichia coli O157:H7 infections with antimicrobial agents is controversial due to an association with potentially fatal sequelae. The production of Shiga toxins is believed to be central to the pathogenesis of this organism. Therefore, decreasing the expression of these...

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Hlavní autoři: Rahal, Elias A, Kazzi, Natalie, Sabra, Ahmad, Abdelnoor, Alexander M, Matar, Ghassan M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180354/
https://ncbi.nlm.nih.gov/pubmed/21906403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-0711-10-34
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