Fibrinogen binding is affected by amino acid substitutions in C-terminal repeat region of fibronectin binding protein A

Fibronectin-binding protein A (FnBPA), a protein displayed on the outer surface of Staphylococcus aureus, has a structured A-domain that binds fibrinogen (Fg) and a disordered repeat-region that binds fibronectin (Fn). Amino acid substitutions in Fn-binding repeats (FnBRs) have previously been linke...

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Publicado no:Sci Rep
Main Authors: Casillas-Ituarte, Nadia N., DiBartola, Alex C., Broughton, Megan J., Pérez-Guzmán, Lumarie, Wheeler, Robert M., Ibaraki, Makoto, Lower, B. Alexis, Dunn, James A., Lower, Brian H., Fowler, Vance G., Hӧӧk, Magnus, McIntyre, Lauren M., Lower, Steven K., Sharma-Kuinkel, Batu K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690874/
https://ncbi.nlm.nih.gov/pubmed/31406152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48031-5
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