Endovascular Infections Caused by Methicillin-Resistant Staphylococcus aureus Are Linked to Clonal Complex-Specific Alterations in Binding and Invasion Domains of Fibronectin-Binding Protein A as Well as the Occurrence of fnbB

Endovascular infections caused by Staphylococcus aureus involve interactions with fibronectin present as extracellular matrix or surface ligand on host cells. We examined the expression, structure, and binding activity of the two major S. aureus fibronectin-binding proteins (FnBPA, FnBPB) in 10 dist...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Xiong, Yan Q., Sharma-Kuinkel, Batu K., Casillas-Ituarte, Nadia N., Fowler, Vance G., Rude, Thomas, DiBartola, Alex C., Lins, Roberto D., Abdel-Hady, Wessam, Lower, Steven K., Bayer, Arnold S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645417/
https://ncbi.nlm.nih.gov/pubmed/26416903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01074-15
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