Amino acid polymorphisms in the fibronectin-binding repeats of fibronectin-binding protein A affect bond strength and fibronectin conformation

The Staphylococcus aureus cell surface contains cell wall-anchored proteins such as fibronectin-binding protein A (FnBPA) that bind to host ligands (e.g. fibronectin; Fn) present in the extracellular matrix of tissue or coatings on cardiac implants. Recent clinical studies have found a correlation b...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Casillas-Ituarte, Nadia N., Cruz, Carlos H. B., Lins, Roberto D., DiBartola, Alex C., Howard, Jessica, Liang, Xiaowen, Höök, Magnus, Viana, Isabelle F. T., Sierra-Hernández, M. Roxana, Lower, Steven K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448106/
https://ncbi.nlm.nih.gov/pubmed/28400484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786012
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