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Interferon-γ induces the cell surface exposure of phosphatidylserine by activating the protein MLKL in the absence of caspase-8 activity

Phosphatidylserine (PS), an anionic phospholipid enriched in the inner leaflet of the plasma membrane, is exposed to the outer leaflet during apoptosis. PS exposure was recently shown to be induced during tumor necrosis factor–induced necroptosis. We herein demonstrated that interferon (IFN)-γ induc...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chen, Jiancheng, Kuroki, Shunsuke, Someda, Masataka, Yonehara, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690710/
https://ncbi.nlm.nih.gov/pubmed/31217278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007161
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