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Interferon-γ induces the cell surface exposure of phosphatidylserine by activating the protein MLKL in the absence of caspase-8 activity

Phosphatidylserine (PS), an anionic phospholipid enriched in the inner leaflet of the plasma membrane, is exposed to the outer leaflet during apoptosis. PS exposure was recently shown to be induced during tumor necrosis factor–induced necroptosis. We herein demonstrated that interferon (IFN)-γ induc...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Chen, Jiancheng, Kuroki, Shunsuke, Someda, Masataka, Yonehara, Shin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690710/
https://ncbi.nlm.nih.gov/pubmed/31217278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007161
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